Millions at Risk: Could Your Blood Clot Medication Be Doing More Harm Than Good?
By
Veronica E.
- Replies 0
Disclaimer: The information provided in this article is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified healthcare providers with any questions you may have regarding a medical condition or before making any changes to your health regimen.
Health is wealth, as the saying goes—but what if a solution meant to protect your health could actually put it at risk? For millions of Americans managing chronic conditions, understanding the risks and benefits of their medications is crucial.
That’s why we’re diving into a topic that could have serious implications for many in our community, particularly those navigating life after a heart attack or other vascular issues.
Could a medication meant to protect your heart actually be putting it at risk?
A widely prescribed blood clot medication has come under scrutiny for its effectiveness and potential risks, sparking serious concerns among experts and patients alike.

The Controversy Surrounding Brilinta
Developed by AstraZeneca, Brilinta (ticagrelor) is designed to prevent life-threatening blood clots that can lead to strokes and heart attacks by reducing the blood’s ability to clot.
Approved by the FDA in 2011, it quickly became a common prescription for individuals with a history of heart attacks or those at high risk for clot-related events.
However, concerns surrounding its approval process and subsequent studies have cast doubt on its safety and efficacy, raising important questions for patients and caregivers alike.
From the start, Brilinta’s FDA approval was controversial. Experts like Dr. Victor Serebruany of Johns Hopkins University have questioned the validity of trial results and the drug’s overall safety and efficacy.

Despite these concerns, an estimated 2 million prescriptions have been written, with the U.S. government spending over $750 million on the drug through Medicare and Medicaid.
Recent research has brought Brilinta’s risks into sharper focus. While it may be better than no treatment at all, some studies suggest it falls short compared to similar medications in preventing severe bleeding, strokes, or deaths from blood clots.
Dr. Peter Doshi’s analysis of original trial data found that American patients taking ticagrelor faced a 27% higher risk of adverse outcomes compared to those on similar drugs.
A 2015 study in Japan reinforced these findings, showing increased rates of severe bleeding, stroke, and death among patients using ticagrelor versus alternative medications.

Even early advocates, like Professor Eric Bates from the University of Michigan, have since reconsidered their support for the drug.
The Call for Justice and Reevaluation
Concerns over Brilinta have led scientists like Dr. Serebruany to call for a Department of Justice investigation into the drug.
A previous inquiry in 2013 was halted, but mounting evidence now suggests it may be time for another look.
Understanding the Medication and Its Costs
For those prescribed Brilinta, the medication is typically taken twice daily for six months to a year following a heart attack, alongside aspirin.
However, the costs can be steep—up to $450 for a 60-tablet bottle without insurance—making it a significant burden for those on a fixed income.
What Should You Do?
If you or a loved one is taking Brilinta, it’s critical to have an informed conversation with your healthcare provider. Discuss the risks, benefits, and potential alternatives to ensure the best care.
Additionally, lifestyle changes like maintaining a healthy weight, quitting smoking, and engaging in regular exercise can help reduce the risk of blood clots naturally.
Here at The GrayVine, we are committed to empowering our readers with the knowledge to make informed health decisions. Stay proactive, advocate for your well-being, and always keep the lines of communication open with your healthcare provider. Together, we can navigate these challenges and prioritize your health and safety.
Have you or someone you know been prescribed Brilinta? Did you experience any side effects or have concerns about the medication? Share your story in the comments below. Your experiences could help others in our community make more informed health decisions!
Health is wealth, as the saying goes—but what if a solution meant to protect your health could actually put it at risk? For millions of Americans managing chronic conditions, understanding the risks and benefits of their medications is crucial.
That’s why we’re diving into a topic that could have serious implications for many in our community, particularly those navigating life after a heart attack or other vascular issues.
Could a medication meant to protect your heart actually be putting it at risk?
A widely prescribed blood clot medication has come under scrutiny for its effectiveness and potential risks, sparking serious concerns among experts and patients alike.

Brilinta, a widely prescribed blood clot medication, faces growing scrutiny over its effectiveness and safety. Image Source: Pexels / Anna Shvets.
The Controversy Surrounding Brilinta
Developed by AstraZeneca, Brilinta (ticagrelor) is designed to prevent life-threatening blood clots that can lead to strokes and heart attacks by reducing the blood’s ability to clot.
Approved by the FDA in 2011, it quickly became a common prescription for individuals with a history of heart attacks or those at high risk for clot-related events.
However, concerns surrounding its approval process and subsequent studies have cast doubt on its safety and efficacy, raising important questions for patients and caregivers alike.
From the start, Brilinta’s FDA approval was controversial. Experts like Dr. Victor Serebruany of Johns Hopkins University have questioned the validity of trial results and the drug’s overall safety and efficacy.

Concerns rise over Brilinta’s effectiveness in preventing strokes and heart attacks, as new studies challenge its safety. Image Source: Henry Schein Special Markets.
Despite these concerns, an estimated 2 million prescriptions have been written, with the U.S. government spending over $750 million on the drug through Medicare and Medicaid.
The Risks and Efficacy of BrilintaRecent research has brought Brilinta’s risks into sharper focus. While it may be better than no treatment at all, some studies suggest it falls short compared to similar medications in preventing severe bleeding, strokes, or deaths from blood clots.
Dr. Peter Doshi’s analysis of original trial data found that American patients taking ticagrelor faced a 27% higher risk of adverse outcomes compared to those on similar drugs.
A 2015 study in Japan reinforced these findings, showing increased rates of severe bleeding, stroke, and death among patients using ticagrelor versus alternative medications.

Blood clots can lead to serious health risks, making effective medication crucial in preventing strokes and heart attacks. Image Source: Pexels / Photo By: Kaboompics.com
Even early advocates, like Professor Eric Bates from the University of Michigan, have since reconsidered their support for the drug.
The Call for Justice and Reevaluation
Concerns over Brilinta have led scientists like Dr. Serebruany to call for a Department of Justice investigation into the drug.
A previous inquiry in 2013 was halted, but mounting evidence now suggests it may be time for another look.
Understanding the Medication and Its Costs
For those prescribed Brilinta, the medication is typically taken twice daily for six months to a year following a heart attack, alongside aspirin.
However, the costs can be steep—up to $450 for a 60-tablet bottle without insurance—making it a significant burden for those on a fixed income.
What Should You Do?
If you or a loved one is taking Brilinta, it’s critical to have an informed conversation with your healthcare provider. Discuss the risks, benefits, and potential alternatives to ensure the best care.
Additionally, lifestyle changes like maintaining a healthy weight, quitting smoking, and engaging in regular exercise can help reduce the risk of blood clots naturally.
Here at The GrayVine, we are committed to empowering our readers with the knowledge to make informed health decisions. Stay proactive, advocate for your well-being, and always keep the lines of communication open with your healthcare provider. Together, we can navigate these challenges and prioritize your health and safety.
Key Takeaways
- Millions of Americans may be at risk of strokes and heart attacks due to concerns over the efficacy of the blood clot medication Brilinta (ticagrelor), which is prescribed to individuals with a history of heart attacks or blood vessel conditions.
- Critics, including doctors and scientists, have questioned the drug's FDA approval in 2011 and subsequent studies suggesting it may not be as effective as other medications in preventing severe bleeding, strokes, and death.
- The drug's effectiveness has been scrutinized after various studies revealed that American patients taking ticagrelor had a 27% higher risk of adverse outcomes compared to those taking similar drugs.
- There have been calls for the Department of Justice to re-examine ticagrelor following an inconclusive investigation that ended in 2014. AstraZeneca has faced criticism but declined to be interviewed for a recent report highlighting these concerns.
Have you or someone you know been prescribed Brilinta? Did you experience any side effects or have concerns about the medication? Share your story in the comments below. Your experiences could help others in our community make more informed health decisions!