Our skin does more than protect us—it communicates with us. And sometimes, what seems like an everyday rash or irritation could be something far more serious.

Here at The GrayVine, we believe staying informed is key to proactive wellness, especially when signs of deeper health issues may be hiding in plain sight.

That’s why we’re taking a closer look at what experts say could be a critical warning sign of liver disease: your skin.



The liver plays a vital role in filtering blood, producing bile, and breaking down toxins.

But when it becomes overworked or damaged—whether by infection, fatty buildup, or toxic overload—the effects ripple through your entire body.

Toxic hepatitis and cirrhosis, two potentially life-threatening liver conditions, can silently progress over time.


Cirrhosis alone is one of the top 10 causes of death in the US, claiming nearly 55,000 lives each year.

And one of the first places signs of liver trouble can show up? Your skin.

The Skin Symptoms You Shouldn’t Ignore​

Dr. Jaban Moore, a functional medicine specialist, recently highlighted several skin symptoms that may point to poor liver function.

These are often overlooked or mistaken for unrelated issues—but being aware of them could make all the difference.

1. Rashes or Dermatitis Around the Mouth​

If you're experiencing persistent redness or irritation around your mouth, it may be more than a cosmetic concern.

According to Dr. Moore, liver dysfunction can reduce your ability to absorb nutrients like zinc and vitamin B2—both essential for healthy skin.

A deficiency can lead to dermatitis, especially in areas like the face and lips.

2. Spider Veins​

Small, web-like red or blue veins—often on the chest, face, or ribs—can be one of the earliest signs of liver dysfunction.

These “spider veins” may indicate changes in blood pressure regulation or hormonal imbalances tied to liver health.

They're more than a cosmetic nuisance—they’re a signal worth noticing.

3. Persistent Itching and Darkened Skin​

When the liver can’t properly process toxins or bile, bile salts may build up in the bloodstream.

This can lead to widespread itching and the development of dark, velvety patches known as acanthosis nigricans, especially around the neck and armpits.

Dr. Moore notes this may also be linked to insulin resistance caused by liver inflammation.

4. Rosacea​

Rosacea—visible as redness or bumps across the nose, cheeks, and forehead—has been linked to non-alcoholic fatty liver disease (NAFLD) and NASH (non-alcoholic steatohepatitis).

While not a direct symptom of liver failure, it may reflect a deeper imbalance.

Dr. Moore points out that liver-related inflammation may affect hormone processing and skin cell behavior, potentially triggering this condition in some individuals.

Why These Signs Matter​

As Dr. Moore explains, "When bile flow is sluggish, the liver gets overwhelmed, hormones become imbalanced, and toxins build up—leading to visible skin symptoms."

Your skin may be offering the first clues that your liver needs help.

And the sooner you recognize the signs, the better your chances of taking corrective action before more serious damage occurs.

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Have you ever had a skin condition that led to a deeper diagnosis? Or perhaps you’ve made lifestyle changes that helped support your liver health? Share your story in the comments—because your experience could help someone else catch the signs early.