This overlooked cancer is rising fast—here’s who’s most at risk

It’s not often talked about. It can be mistaken for something minor.

But new research shows this type of cancer is quietly on the rise—and one group of Americans is seeing the sharpest increase.

Now, experts say awareness and early action may be more important than ever.



A new study presented at Digestive Disease Week found that anal cancer cases are climbing, particularly among older women.

Researchers analyzed data from the National Cancer Institute between 2017 and 2021.


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Anal cancer cases are climbing, particularly among older women. Image source: National Cancer Institute / Unsplash


They discovered that anal cancer rates rose by 2.9% in women and 1.6% in men during that period.

But the biggest increase was in white and Hispanic women over 65—a group not traditionally considered high risk.



According to lead author Dr. Ashley Robinson, an internal medicine resident at Advocate Lutheran General Hospital, white women over 65 saw a 4.3% rise, while Hispanic women in that same age group saw an annual increase of 1.7%.

If trends continue, experts warn that cases could double for women over 65 in less than 17 years.

Anal cancer forms in the anal canal, the part of the body located at the end of the rectum.

Common symptoms include:
  • Anal bleeding
  • Pain or itching
  • Unusual lumps or growths
  • Blood in poo
Because these symptoms often mimic hemorrhoids, many people may not recognize the warning signs early.



Also read: The sneaky signs of cancer most men miss—Would you recognize them before it’s too late?

Though the study didn’t confirm a specific cause, researchers point to HPV (human papillomavirus) as a key risk factor.

The HPV vaccine, introduced in the US in 2006, helps protect against multiple cancers, including anal, cervical, and some head and neck cancers.

But many older women were not eligible for the vaccine during its rollout, meaning they may lack that key layer of protection today.

Dr. Robinson emphasized, “Rates of anal cancer are rising fastest among white and Hispanic women over 65—groups not traditionally considered high risk.”



The Centers for Disease Control and Prevention (CDC) recommends the HPV vaccine for individuals up to age 26, ideally before becoming sexually active.

That’s because the vaccine is most effective when given before exposure to the virus.

HPV is spread primarily through skin-to-skin contact, often during intimate activity.

In the UK, HPV vaccination is offered to children ages 12 to 13 as part of routine public health efforts.



Also read: New study uncovers disturbing link between a household favorite and rising cancer cases

Dr. Robinson believes this new data highlights a potential gap in care:

“It’s crucial that we promote HPV vaccination as a key tool for preventing anal cancer,” she said, “while also keeping health care providers informed as screening guidelines evolve.”

Currently, there is no standard screening protocol for anal cancer in older women.

But findings like these may push public health leaders to reassess who should be screened—and when.

“These findings highlight specific patient groups who may benefit from targeted screening for anal HPV and anal cancer,” Dr. Robinson added.

Read next: 5 Everyday Habits You Must Avoid Right Now to Outsmart Colorectal Cancer, According to Experts!
Key Takeaways

  • Anal cancer is rising fastest among white and Hispanic women over 65, according to a recent study.
  • Cases in women rose by 2.9% between 2017 and 2021, with the highest increases seen in older adults.
  • HPV infection is the leading risk factor for anal cancer, and many in the affected group were never vaccinated.
  • Experts are urging increased awareness, vaccination promotion, and a possible reexamination of screening guidelines.

Do you think cancer screenings should be expanded based on new research? Have you or someone you know been affected by HPV-related illness? Share your story or thoughts in the comments—your experience may help someone else.
 

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